Urabrelimab
Urabrelimab (SRF231) is a fully human anti-CD47 monoclonal antibody that blocks the CD47-SIRP interaction[1].
Product Specifications
CAS Number
[2249722-58-3]
Product Name Alternative
SRF-231; SRF231
UNSPSC
12352203
Target
CD47; Interleukin Related
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/urabrelimab.html
Purity
99.487
Solubility
H2O
Smiles
[Urabrelimab]
Molecular Weight
(145.12 kDa)
References & Citations
[1]Holland P M, et al. CD47 monoclonal antibody SRF231 is a potent inducer of macrophage-mediated tumor cell phagocytosis and reduces tumor burden in murine models of hematologic malignancies. 2016.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 1
Available Sizes
Curated Selection
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