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PAX6 Polyclonal Antibody

Product Specifications

Background

This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms.

Abbreviation

PAX6

UniProt

P26367

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant fusion protein of human PAX6 (NP_000271.1) .

Target

AN; AN2; ASGD5; D11S812E; FVH1; MGDA; WAGR; PAX6

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IF

Field of Research

Cancer; Epigenetics and Nuclear Signaling; Developmental Biology; Neuroscience; Stem Cells

Purification

Affinity purification

Concentration

1mg/mL

Dilution

IF 1:50-1:200

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product Datasheet

https://789.bio/ea/vuiqus

Product MSDS

https://789.bio/eb/W94ez1

Citation 01

https://www.mdpi.com/1185940

Isotype

IgG

Available Sizes

Curated Selection

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