TIM-3/HAVCR2 Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.
Abbreviation
TIM-3/HAVCR2
UniProt
Q8TDQ0
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant fusion protein of human TIM-3/HAVCR2 (NP_116171.3) .
Target
HAVCR2; CD366; HAVcr-2; KIM-3; TIM3; TIMD-3; TIMD3; Tim-3
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Immunology
Purification
Affinity purification
Concentration
1mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
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