(KO Validated) EIF4E Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants.
Abbreviation
EIF4E
UniProt
P06730
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
A synthetic peptide of human EIF4E (NP_001959.1) .
Target
AUTS19; CBP; EIF4E1; EIF4EL1; EIF4F; eIF-4E; EIF4E
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC; IF
Field of Research
Cancer; Epigenetics and Nuclear Signaling
Purification
Affinity purification
Concentration
1mg/mL
Dilution
IHC 1:50-1:100; IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Frequently Asked Questions
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