CD27 Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Abbreviation
CD27
UniProt
P26842
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant fusion protein of human CD27 (NP_001233.1) .
Target
CD27; S152; S152. LPFS2; T14; TNFRSF7; Tp55; S152.LPFS2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC; IF
Field of Research
Cancer; Immunology; Stem Cells
Purification
Affinity purification
Concentration
1mg/mL
Dilution
IHC 1:50-1:200; IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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