KEAP1 Polyclonal Antibody
Product Specifications
Background
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
Abbreviation
KEAP1
UniProt
Q14145
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant fusion protein of human KEAP1 (NP_036421.2) .
Target
KEAP1; INrf2; KLHL19
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC; IF
Field of Research
Cancer; Epigenetics and Nuclear Signaling
Purification
Affinity purification
Concentration
1mg/mL
Dilution
IHC 1:50-1:200; IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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