CD11B Polyclonal Antibody
Product Specifications
Background
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3') . The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.
Abbreviation
CD11B
UniProt
P11215
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant fusion protein of human CD11B (NP_001139280.1) .
Target
CD11B; CR3A; MAC-1; MAC1A; MO1A; SLEB6; ITGAM; CD11b/ITAM
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IF
Field of Research
Cancer; Neuroscience; Signal Transduction; Stem Cells; Tags and Cell Markers
Purification
Affinity purification
Concentration
1mg/mL
Dilution
IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Citation 01
https://www.sciencedirect.com/science/article/pii/S0024320519303807
Isotype
IgG
Available Sizes
Curated Selection
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