MITF Polyclonal Antibody
Product Specifications
Background
This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
Abbreviation
MITF
UniProt
O75030
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant fusion protein of human MITF (NP_937801.1) .
Target
MITF; CMM8; COMMAD; MI; WS2; WS2A; bHLHe32
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Epigenetics and Nuclear Signaling; Immunology
Purification
Affinity purification
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
40kDa/46kDa/52kDa/55kDa/56kDa/57kDa/58kDa
Observed Molecular Weight
65kDa
Citation 01
https://www.sciencedirect.com/science/article/pii/S0923181120302000
Isotype
IgG
Available Sizes
Curated Selection
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