Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

ASC / TMS1 Polyclonal Antibody

Product Specifications

Background

This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD) . The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene.

Abbreviation

ASC / TMS1

UniProt

Q9ULZ3

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant fusion protein of human ASC / TMS1 (NP_037390.2) .

Target

PYCARD; ASC; CARD5; TMS; TMS-1; TMS1; PYD and CARD domain containing; ASC / TMS1

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IF

Field of Research

Cancer; Cell Biology

Purification

Affinity purification

Concentration

1mg/mL

Dilution

WB 1:500-1:2000; IF 1:50-1:200

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

15kDa/19kDa/21kDa

Observed Molecular Weight

22kDa

Citation 01

https://www.sciencedirect.com/science/article/pii/S1567576923002242

Citation 02

https://www.nature.com/articles/s41598-022-04785-z

Citation 03

https://journals.lww.com/neuroreport/Fulltext/2021/06020/Protective_effects_of_melatonin_on_the_white.1.aspx?context=LatestArticles

Isotype

IgG

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Azurin Goat Polyclonal Antibody
AB0048-100 300 µg

Azurin Goat Polyclonal Antibody

Sign In for Pricing
View Details
Beta-2 Microglobulin (B2M) (BBM.1), CF647 conjugate, 0.1mg/mL
BNC470142-100 1x 100 µL

Beta-2 Microglobulin (B2M) (BBM.1), CF647 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
1-Anthracenecarboxylic Acid
TRC-A637258-50MG 50 mg

1-Anthracenecarboxylic Acid

Sign In for Pricing
View Details
NeuN (RBFOX3) Mouse Monoclonal Antibody [Clone ID: A60]
AM10122SU-N 1 mL

NeuN (RBFOX3) Mouse Monoclonal Antibody [Clone ID: A60]

Sign In for Pricing
View Details
Pea3 (ETV4) (NM_001986) Human Over-expression Lysate
LY419608 100 µg

Pea3 (ETV4) (NM_001986) Human Over-expression Lysate

Sign In for Pricing
View Details
Human COL15 (Collagen Type XV) CLIA Kit
E-CL-H0552-01 24 Tests

Human COL15 (Collagen Type XV) CLIA Kit

Sign In for Pricing
View Details