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Bcl-2 Polyclonal Antibody

Product Specifications

Background

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.

Abbreviation

Bcl-2

UniProt

P10415

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

A synthetic peptide of human Bcl-2

Target

Bcl-2; PPP1R50; BCL2

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC; IF

Field of Research

Cancer; Cell Biology; Metabolism; Signal Transduction

Purification

Affinity purification

Concentration

1mg/mL

Dilution

WB 1:500-1:2000; IHC 1:50-1:100; IF 1:50-1:100

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

22kDa/26kDa

Observed Molecular Weight

24kDa/26kDa

Citation 01

https://www.mdpi.com/1806946

Citation 02

https://www.mdpi.com/1281194

Citation 03

https://link.springer.com/article/10.1007/s11356-023-26018-0

Citation 04

https://onlinelibrary.wiley.com/doi/abs/10.1111/jre.12973

Citation 05

https://www.sciencedirect.com/science/article/pii/S0300483X18303937

Citation 06

https://www.mdpi.com/2080828

Citation 07

https://www.sciencedirect.com/science/article/pii/S0006291X19321874

Citation 08

https://bmccomplementmedtherapies.biomedcentral.com/articles/10.1186/s12906-019-2768-1

Citation 09

https://link.springer.com/article/10.1007/s12011-018-1587-4

Isotype

IgG

Available Sizes

Curated Selection

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