BAK1 Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
Abbreviation
BAK1
UniProt
Q16611
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
A synthetic peptide of human BAK1 (NP_001179.1) .
Target
BAK1; BAK; BAK-LIKE; BCL2L7
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IF
Field of Research
Cancer; Cell Biology
Purification
Affinity purification
Concentration
1mg/mL
Dilution
WB 1:500-1:2000; IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/vsxqs8
Product MSDS
https://789.bio/eb/9aH04C
Calculated Molecular Weight
16kDa/23kDa
Observed Molecular Weight
26kDa
Isotype
IgG
Available Sizes
Curated Selection
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