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BAK1 Polyclonal Antibody

Product Specifications

Background

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

Abbreviation

BAK1

UniProt

Q16611

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

A synthetic peptide of human BAK1 (NP_001179.1) .

Target

BAK1; BAK; BAK-LIKE; BCL2L7

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IF

Field of Research

Cancer; Cell Biology

Purification

Affinity purification

Concentration

1mg/mL

Dilution

WB 1:500-1:2000; IF 1:50-1:200

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

16kDa/23kDa

Observed Molecular Weight

26kDa

Isotype

IgG

Available Sizes

Curated Selection

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