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IQGAP1 Polyclonal Antibody

Product Specifications

Background

This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.

Abbreviation

IQGAP1

UniProt

P46940

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Synthetic peptide of human IQGAP1

Target

HUMORFA01; IQ motif containing GTPase activating protein 1; IQGA1; Iqgap1; KIAA0051; p195; Ras GTPase activating like protein 1; Ras GTPase-activating-like protein IQGAP1; RasGAP-like with IQ motifs; SAR1

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cancer; Signal Transduction

Purification

Antigen affinity purification

Concentration

0.5 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:25-1:100

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

189 kDa

Observed Molecular Weight

Refer to figures

Isotype

IgG

Available Sizes

Frequently Asked Questions

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