IFNB1 Polyclonal Antibody
Product Specifications
Background
This gene encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection.
Abbreviation
IFNB1
UniProt
P01574
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human IFNB1
Target
Beta-interferon; Fibroblast interferon; IFB; IFF; IFN beta; IFN-beta; IFNB 1; IFNB; IFNB; IFNB1; Interferon beta 1 fibroblast; Interferon beta; Interferon beta precursor; MGC96956
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cardiovascular; Immunology
Purification
Antigen affinity purification
Concentration
1.1 mg/mL
Dilution
IHC 1:30-1:150
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Frequently Asked Questions
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