GZMM Polyclonal Antibody
Product Specifications
Background
GZMM (Granzyme M) is a Protein Coding gene. Diseases associated with GZMM include Adrenal Insufficiency, Congenital, With 46Xy Sex Reversal, Partial Or Complete and Congenital Adrenal Insufficiency. Among its related pathways are Innate Immune System and Granzyme Pathway. GO annotations related to this gene include serine-type endopeptidase activity and endopeptidase activity. An important paralog of this gene is CFD.Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and the protein encoded by this gene, granzyme M. Two transcript variants encoding different isoforms have been found for this gene.
Abbreviation
GZMM
UniProt
P51124
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide of human GZMM
Target
GRAM; Granzyme M (lymphocyte met ase 1) ; Granzyme M; GranzymeM; GZM M; Gzmm; HU Met 1; HU-Met-1; LMET 1; LMET1; Lymphocyte met ase 1; MET 1; Met 1 serine protease; Met ase; Met-1 serine protease; Met-ase; MET1; Met1 serine protease; Natural killer cell granular protease
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cell Biology
Purification
Antigen affinity purification
Concentration
0.6 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:20-1:100
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
28 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG
Available Sizes
Curated Selection
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