BAG2 Polyclonal Antibody
Product Specifications
Background
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
Abbreviation
BAG2
UniProt
O95816
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human BAG2
Target
BAG 2; BAG family molecular chaperone regulator 2; BAG-2; BAG-family molecular chaperone regulator-2; Bag2; BAG2; BCL 2 associated athanogene 2; Bcl-2-associated athanogene 2; BCL2 associated athanogene 2; BCL2-associated athanogene 2; dJ417I1.2 (BAG family molecular chaperone regulator 2) ; dJ417I1.2; KIAA0576; MGC149462; OTTHUMP00000016668
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cell Biology; Signal Transduction; Cancer; Metabolism
Purification
Antigen affinity purification
Concentration
0.8 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:20-1:100
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
24 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG
Available Sizes
Frequently Asked Questions
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