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ATG16L1 Polyclonal Antibody

Product Specifications

Background

ATG16L1 (Autophagy Related 16 Like 1) is a Protein Coding gene. Diseases associated with ATG16L1 include Inflammatory Bowel Disease 10 and Inflammatory Bowel Disease. Among its related pathways are Autophagy Pathway and Senescence and Autophagy in Cancer. GO annotations related to this gene include identical protein binding. An important paralog of this gene is ATG16L2.The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10) . Several transcript variants encoding different isoforms have been found for this gene.

Abbreviation

ATG16L1

UniProt

Q676U5

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Synthetic peptide of human ATG16L1

Target

A16L1; APG16 like 1; APG16-like 1; APG16L; APG16L beta; ATG16 autophagy related 16 like 1; ATG16 autophagy related 16-like 1 (S. cerevisiae) ; ATG16A; ATG16L; Atg16l1; Autophagy related protein 16 1; Autophagy-related protein 16-1; FLJ00045; FLJ10035; FLJ10828; FLJ22677; IBD10; OTTHUMP00000164391; OTTHUMP00000164393; OTTHUMP00000165876; OTTHUMP00000165877; WD repeat domain 30; WDR30

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cancer; Cell Biology; Cardiovascular; Metabolism; Neuroscience; Signal Transduction

Purification

Antigen affinity purification

Concentration

0.8 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:30-1:150

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

68 kDa

Observed Molecular Weight

Refer to figures

Isotype

IgG

Available Sizes

Frequently Asked Questions

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