STARD4 Polyclonal Antibody
Product Specifications
Background
Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE) -binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423) . Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617) . STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]) .
Abbreviation
STARD4
UniProt
Q96DR4
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human STARD4
Target
4632419C16Rik;9030213J02Rik; AA517649; AW324468; StAR related lipid transfer (START) domain containing 4; StAR-related lipid transfer protein 4; STAR4; StARD4; START domain containing 4 sterol regulated; START domain-containing protein 4
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cardiovascular; Metabolism; Signal transduction
Purification
Antigen affinity purification
Concentration
1.2 mg/mL
Dilution
IHC 1:25-1:100
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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