HTRA1 Polyclonal Antibody
Product Specifications
Background
This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7.
Abbreviation
HTRA1
UniProt
Q92743
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide of human HTRA1
Target
ARMD7; CARASIL; High-temperature requirement A serine peptidase 1; HtrA; HtrA serine peptidase 1; HTRA1; HTRA1; IGFBP5 protease; L56; ORF480; Protease serine 11 (IGF binding) ; protease serine 11; PRSS11 ; Serine protease 11; Serine protease HTRA1; Serine protease HTRA1 precursor
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Signal transduction
Purification
Antigen affinity purification
Concentration
0.9 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:40-1:200
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
51 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG
Available Sizes
Frequently Asked Questions
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