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PSCA Polyclonal Antibody

Product Specifications

Background

PSCA (Prostate Stem Cell antigen) is a cell surface antigen, which is overexpressed in ~40% of primary prostate cancers and in as many as 100% of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical zenograft model indicating that PSCA may have utility as a prognostic marker and/or therapeutic target in prostate cancer.

Abbreviation

PSCA

UniProt

O43653

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Synthetic peptide of human PSCA

Target

PRO 232; PRO232; Prostate stem cell antigen

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Stem Cells

Purification

Antigen affinity purification

Concentration

0.78 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:20-1:100

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

13 kDa

Observed Molecular Weight

Refer to figures

Isotype

IgG

Available Sizes

Curated Selection

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