PSCA Polyclonal Antibody
Product Specifications
Background
PSCA (Prostate Stem Cell antigen) is a cell surface antigen, which is overexpressed in ~40% of primary prostate cancers and in as many as 100% of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical zenograft model indicating that PSCA may have utility as a prognostic marker and/or therapeutic target in prostate cancer.
Abbreviation
PSCA
UniProt
O43653
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human PSCA
Target
PRO 232; PRO232; Prostate stem cell antigen
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Stem Cells
Purification
Antigen affinity purification
Concentration
0.78 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:20-1:100
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
13 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG
Available Sizes
Frequently Asked Questions
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