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CD63 Polyclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.

Abbreviation

CD63

UniProt

P08962

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Synthetic peptide of human CD63

Target

Lysosomal associated membrane protein 3; CD 63; CD63; CD63 antigen (melanoma 1 antigen) ; CD63 antigen; CD63 antigen melanoma 1 antigen; CD63 molecule; CD63; gp55; Granulophysin; LAMP 3; LAMP-3; LAMP3; LIMP; Lysosomal-associated membrane protein 3; Lysosome associated membrane glycoprotein 3; Mast cell antigen AD1; ME491; Melanoma 1 antigen; Melanoma associated antigen ME491; Melanoma associated antigen MLA1; Melanoma-associated antigen ME491; MGC72893; MLA 1; MLA1; NGA; Ocular melanoma associated antigen; Ocular melanoma-associated antigen; OMA81H; PTLGP40; Tetraspanin 30; Tetraspanin-30; Tspan 30; Tspan-30; TSPAN30

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB

Field of Research

Cancer; Cardiovascular; Immunology; Tags and Cell Markers

Purification

Antigen affinity purification

Concentration

0.7 mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

26 kDa

Observed Molecular Weight

Refer to figures

Citation 01

https://jcs.biologists.org/content/early/2019/10/17/jcs.233239.abstract

Citation 02

https://link.springer.com/article/10.1007/s12247-021-09566-1

Isotype

IgG

Available Sizes

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