CD63 Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.
Abbreviation
CD63
UniProt
P08962
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human CD63
Target
Lysosomal associated membrane protein 3; CD 63; CD63; CD63 antigen (melanoma 1 antigen) ; CD63 antigen; CD63 antigen melanoma 1 antigen; CD63 molecule; CD63; gp55; Granulophysin; LAMP 3; LAMP-3; LAMP3; LIMP; Lysosomal-associated membrane protein 3; Lysosome associated membrane glycoprotein 3; Mast cell antigen AD1; ME491; Melanoma 1 antigen; Melanoma associated antigen ME491; Melanoma associated antigen MLA1; Melanoma-associated antigen ME491; MGC72893; MLA 1; MLA1; NGA; Ocular melanoma associated antigen; Ocular melanoma-associated antigen; OMA81H; PTLGP40; Tetraspanin 30; Tetraspanin-30; Tspan 30; Tspan-30; TSPAN30
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Cardiovascular; Immunology; Tags and Cell Markers
Purification
Antigen affinity purification
Concentration
0.7 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
26 kDa
Observed Molecular Weight
Refer to figures
Citation 01
https://jcs.biologists.org/content/early/2019/10/17/jcs.233239.abstract
Citation 02
https://link.springer.com/article/10.1007/s12247-021-09566-1
Isotype
IgG
Available Sizes
Curated Selection
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