RBM4 Polyclonal Antibody

RBM4, RNA-binding motif protein4, contains 2 RRM-type RNA-binding motif and a retroviral-type (RT) zinc finger. RNA-binding factor participates in number of aspects of cellular processes such as alternative splicing of pre-mRNA and translation regulation. RBM4 recruits eIF4A1 to stimulate IRES-dependent translation in responds to cellular stress. Once assembled at the rHRE, the HIF2A-RBM4-eIF4E2 complex captures the 5-prime cap and targets mRNAs to polysomes for active translation, thereby evading hypoxia-induced repression of protein synthesis.

Dkfzp547k0918; hLark; lark; Lark homolog; lark homologue; mgc75138; RBM4; rbm4 lark; RBM4; RNA binding motif 4; RNA binding motif 4a; RNA-binding motif protein 4; RNA-binding motif protein 4a; RNA-binding protein 4