RDH5 Polyclonal Antibody

This gene encodes an enzyme belonging to the short-chain dehydrogenases/reductases (SDR) family. This retinol dehydrogenase functions to catalyze the final step in the biosynthesis of 11-cis retinaldehyde, which is the universal chromophore of visual pigments. Mutations in this gene cause autosomal recessive fundus albipunctatus, a rare form of night blindness that is characterized by a delay in the regeneration of cone and rod photopigments. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S1 (biogenesis of lysosomal organelles complex-1, subunit 1) gene.

11 cis RDH;11 cis retinol dehydrogenase;9 cis retinol specific dehydrogenase; FLJ39337; FLJ97089; HSD17B9; RDH 5; RDH1; Retinol dehydrogenase 1; Retinol dehydrogenase 5 (11 cis/9 cis) ; Retinol dehydrogenase 5; SDR9C5; Short chain dehydrogenase/reductase family 9C member 5