RITA1 Polyclonal Antibody
Product Specifications
Background
Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.
Abbreviation
RITA1
UniProt
Q96K30
Host
Rabbit
Reactivity
Human
Immunogen
Fusion protein of human RITA1
Target
C12orf52 ; Chromosome 12 open reading frame 52 ; RBPJ interacting and tubulin associated 1; RBPJ interacting and tubulin associated protein 1; RBPJ-interacting and tubulin-associated protein; RITA; RITA
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Developmental biology; Neuroscience; Signal transduction; Stem cells
Purification
Antigen affinity purification
Concentration
0.9 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
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