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THG1L Polyclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a mitochondrial protein that is induced by high levels of glucose and is associated with diabetic nephropathy. The encoded protein appears to increase mitochondrial biogenesis, which could lead to renal fibrosis. Another function of this protein is that of a guanyltransferase, adding GMP to the 5' end of tRNA (His) . Several transcript variants encoding different isoforms have been found for this gene.

Abbreviation

THG1L

UniProt

Q9NWX6

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Fusion protein of human THG1L

Target

ICF45; Interphase cytoplasmic foci protein 45; Probable tRNA (His) guanylyltransferase; THG1; THG1L; tRNA histidine guanylyltransferase 1 like (S. cerevisiae) ; tRNA-histidine guanylyltransferase

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cell Biology

Purification

Antigen affinity purification

Concentration

0.9 mg/mL

Dilution

IHC 1:50-1:200

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

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