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TMED10 Polyclonal Antibody

Product Specifications

Background

This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.

Abbreviation

TMED10

UniProt

P49755

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Fusion protein of human TMED10

Target

1110014C03Rik ;21 kDa transmembrane trafficking protein;21 kDa transmembrane-trafficking protein; MGC102351; p23; p24 family protein delta 1; p24 family protein delta-1; p24 (DELTA) ; p24delta; p24delta1; S31I125; S31III125; TMED 10; Tmed10; TMEDA; Tmp 21 I; Tmp 21; Tmp 21 I; Tmp-21-I; Transmembrane emp24 domain containing protein 10; Transmembrane emp24 domain-containing protein 10; Transmembrane emp24-like trafficking protein 10 (yeast) ; Transmembrane protein Tmp21; Transmembrane trafficking protein 21kD

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cancer; Neuroscience; Signal transduction

Purification

Antigen affinity purification

Concentration

0.9 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:50-1:200

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

25 kDa

Observed Molecular Weight

Refer to figures

Isotype

IgG

Available Sizes

Curated Selection

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