MRPL42 Polyclonal Antibody
Product Specifications
Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a protein identified as belonging to both the 28S and the 39S subunits. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 4q, 6p, 6q, 7p, and 15q.
Abbreviation
MRPL42
UniProt
Q9Y6G3
Host
Rabbit
Reactivity
Human; Rat
Immunogen
Fusion protein of human MRPL42
Target
28S ribosomal protein S32;39S ribosomal protein L31;39S ribosomal protein L42; HSPC204 ; L31mt; L42mt; mitochondrial; Mitochondrial ribosomal protein L42; Mitochondrial ribosomal protein S32; MRP L31; MRP L42; MRP S32 ; MRP-L31; MRP-L42; MRP-S32; MRPL31 ; Mrpl42; MRPS32 ; PTD007 ; RM42; RPML31 ; S32mt
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Epigenetics and Nuclear Signaling; Metabolism
Purification
Antigen affinity purification
Concentration
1.02 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:200
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
17 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG
Available Sizes
Curated Selection
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