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SIGLEC6 Polyclonal Antibody

Product Specifications

Background

TheSIGLEC6gene to 19q13.3, which is where the CD33 gene is located. Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. Expressed at high levels in placenta (cyto- and syncytiotrophoblastic cells) and at lower levels in spleen, peripheral blood leukocytes (predominantly B-cells) and small intestine.

Abbreviation

SIGLEC6

UniProt

O43699

Host

Rabbit

Reactivity

Human

Immunogen

Fusion protein of human SIGLEC6

Target

CD327; CD33 antigen-like 1; CD33L; CD33L1; CD33L2; CDw327; OB-BP1; OBBP1; Obesity-binding protein 1; Sialic acid-binding Ig-like lectin 6; SIGL6; Siglec-6; SIGLEC6

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Immunology

Purification

Antigen affinity purification

Concentration

0.78 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:40-1:200

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

50 kDa

Observed Molecular Weight

Refer to figures

Isotype

IgG

Available Sizes

Frequently Asked Questions

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