SIGLEC6 Polyclonal Antibody
Product Specifications
Background
TheSIGLEC6gene to 19q13.3, which is where the CD33 gene is located. Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. Expressed at high levels in placenta (cyto- and syncytiotrophoblastic cells) and at lower levels in spleen, peripheral blood leukocytes (predominantly B-cells) and small intestine.
Abbreviation
SIGLEC6
UniProt
O43699
Host
Rabbit
Reactivity
Human
Immunogen
Fusion protein of human SIGLEC6
Target
CD327; CD33 antigen-like 1; CD33L; CD33L1; CD33L2; CDw327; OB-BP1; OBBP1; Obesity-binding protein 1; Sialic acid-binding Ig-like lectin 6; SIGL6; Siglec-6; SIGLEC6
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Immunology
Purification
Antigen affinity purification
Concentration
0.78 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:40-1:200
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
50 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG
Available Sizes
Curated Selection
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