JPT1 Polyclonal Antibody
Product Specifications
Background
Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408) . Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422) . Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365) . Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (PubMed:22155408) .
Abbreviation
JPT1
UniProt
Q9UK76
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Fusion protein of human JPT1
Target
Androgen regulated protein 2; Androgen-regulated protein 2; ARM2; Hematological and neurological expressed 1; Hematological and neurological expressed 1 protein; HN1; HN1; HN1A
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cell Biology
Purification
Antigen affinity purification
Concentration
0.66 mg/mL
Dilution
IHC 1:30-1:150
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
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