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HIST1H2BK Polyclonal Antibody

Product Specifications

Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-dependent histone that is a member of the histone H2B family. The protein encoded is an antimicrobial protein with antibacterial and antifungal activity. Two transcripts that encode the same protein have been identified for this gene, which is found in the histone microcluster on chromosome 6p21.33.

Abbreviation

HIST1H2BK

UniProt

O60814

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Fusion protein of human HIST1H2BK

Target

H2B histone family member T ; H2B K; H2B/S ; H2BFAiii ; H2BFT; HIRA-interacting protein 1 ; HIRIP1; HIST1H2BK; Histone family member; Histone H2B type 1-K

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Epigenetics and Nuclear Signaling

Purification

Antigen affinity purification

Concentration

1.08 mg/mL

Dilution

IHC 1:40-1:200

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

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