PPOX Polyclonal Antibody

Product Specifications

Background

This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.

Abbreviation

PPOX

UniProt

P50336

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Fusion protein of human PPOX

Target

MGC8485; PPO; PPOX; PPOX; Protoporphyrinogen oxidase; V290M; Variegate porphyria; VP

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cancer; Metabolism; Tags and Cell Markers

Purification

Antigen affinity purification

Concentration

0.78 mg/mL

Dilution

IHC 1:50-1:300

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

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