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QDPR Polyclonal Antibody

Product Specifications

Background

This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.

Abbreviation

QDPR

UniProt

P09417

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Fusion protein of human QDPR

Target

6;7 dihydropteridine reductase; DHPR; DHPR; Dihydropteridine reductase; HDHPR; HPR; PKU2; Qdpr; Quinoid dihydropteridine reductase; SDR33C1; Short chain dehydrogenase/reductase family 33C; member 1

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Metabolism; Signal transduction

Purification

Antigen affinity purification

Concentration

1.2 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:50-1:200

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product Datasheet

https://789.bio/ea/1xyuyd

Product MSDS

https://789.bio/eb/PWTqDG

Calculated Molecular Weight

26 kDa

Observed Molecular Weight

Refer to figures

Isotype

IgG

Available Sizes

Curated Selection

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