HBG1/HBG2 Polyclonal Antibody
Product Specifications
Background
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1) . The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.
Abbreviation
HBG1/HBG2
UniProt
P69891, P69892
Host
Rabbit
Reactivity
Human
Immunogen
Fusion protein of human HBG1/HBG2
Target
A gamma globin; G gamma globin; Gamma 1 globin; Gamma 2 globin; Gamma A hemoglobin; Gamma globin; Hb F Agamma; Hb F Ggamma; hbfagamma; hbfggamma; HBG 1; HBG 2; HBG1; HBG2; HBGA; HBGR; Hemoglobin gamma 1 chain ; Hemoglobin gamma 2 chain ; Hemoglobin gamma A; Hemoglobin gamma A chain ; Hemoglobin gamma G; Hemoglobin gamma G chain ; Hemoglobin gamma regulator of; Hemoglobin subunit gamma 1; Hemoglobin subunit gamma 2; HSGGL 1; HSGGL1; Methemoglobin; PRO 2979; PRO2979
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cardiovascular
Purification
Antigen affinity purification
Concentration
0.84 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:300
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/ysgxsk
Product MSDS
https://789.bio/eb/aX9OSK
Calculated Molecular Weight
16 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG
Available Sizes
Curated Selection
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