PLEKHA1 Polyclonal Antibody

This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.

OTTHUMP00000020651; PH domain containing family A member 1; PH domain-containing family A member 1; PKHA1; Pleckstrin homology domain containing A1; Pleckstrin homology domain containing family A member 1; Pleckstrin homology domain containing; family A (phosphoinositide binding specific) member; Pleckstrin homology domain-containing family A member 1; PLEKHA1; Tandem PH domain containing protein 1; Tandem PH domain-containing protein 1; TAPP 1; TAPP-1; TAPP1