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ZFP36 Polyclonal Antibody

Product Specifications

Background

MRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE) -containing mRNAs. Acts by specifically binding ARE-containing mRNAs and promoting their degradation. Recruits deadenylase CNOT7 (and probably the CCR4-NOT complex) via association with CNOT1. Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF) . Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF) .

Abbreviation

ZFP36

UniProt

P26651

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Fusion protein of human ZFP36

Target

G0/G1 switch regulatory protein 24; G0S24; GOS24; Growth factor-inducible nuclear protein NUP475; NUP475; Protein TIS11A; RNF162A; TIS 11; TIS11; TIS11A; Tristetraprolin; Tristetraproline; TTP; TTP; Zfp-36; ZFP36; Zinc finger protein 36; Zinc finger protein 36 homolog; Zinc finger protein 36; C3H type; homolog (mouse) ; Zinc finger protein; C3H type; 36 homolog

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cancer; Epigenetics and Nuclear Signaling; Immunology; Neuroscience; Signal transduction

Purification

Antigen affinity purification

Concentration

0.8 mg/mL

Dilution

IHC 1:40-1:200

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

Frequently Asked Questions

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