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HNRNPH2 Polyclonal Antibody

Product Specifications

Background

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) . These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that binds to RNAs. It is very similar to the family member HNRPH1. This gene is thought to be involved in Fabray disease and X-linked agammaglobulinemia phenotype. Alternative splicing results in multiple transcript variants encoding the same protein. Read-through transcription between this locus and the ribosomal protein L36a gene has been observed.

Abbreviation

HNRNPH2

UniProt

P55795

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Fusion protein of human HNRNPH2

Target

FTP 3; FTP-3; FTP3; Heterogeneous nuclear ribonucleoprotein H''; heterogeneous nuclear ribonucleoprotein H2 (H') ; Heterogeneous nuclear ribonucleoprotein H2; HNRH2; hnRNP H''; hnRNP H2; hnRNPH'; HNRNPH2; HNRPH'; HNRPH2

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Purification

Antigen affinity purification

Concentration

0.5 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:30-1:150

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

49 kDa

Observed Molecular Weight

Refer to figures

Isotype

IgG

Available Sizes

Curated Selection

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