HNRNPH2 Polyclonal Antibody
Product Specifications
Background
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) . These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that binds to RNAs. It is very similar to the family member HNRPH1. This gene is thought to be involved in Fabray disease and X-linked agammaglobulinemia phenotype. Alternative splicing results in multiple transcript variants encoding the same protein. Read-through transcription between this locus and the ribosomal protein L36a gene has been observed.
Abbreviation
HNRNPH2
UniProt
P55795
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Fusion protein of human HNRNPH2
Target
FTP 3; FTP-3; FTP3; Heterogeneous nuclear ribonucleoprotein H''; heterogeneous nuclear ribonucleoprotein H2 (H') ; Heterogeneous nuclear ribonucleoprotein H2; HNRH2; hnRNP H''; hnRNP H2; hnRNPH'; HNRNPH2; HNRPH'; HNRPH2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:30-1:150
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
49 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG
Available Sizes
Curated Selection
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