WDR77 Polyclonal Antibody
Product Specifications
Background
WDR77 is a component of the 20S PRMT5 (MIM 604045) -containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins (see MIM 601061) . This modification targets Sm proteins to the survival of motor neurons (SMN) complex (see MIM 600354) for assembly into small nuclear ribonucleoprotein core particles (Friesen et al., 2002 [PubMed 11756452]) .
Abbreviation
WDR77
UniProt
Q9BQA1
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Fusion protein of human WDR77
Target
2610312E17Rik; Androgen receptor cofactor p44; C79984; HKMT1069; MEP 50; MEP-50; MEP50; MEP50; Methylosome protein 50; MGC2722; Nbla10071; p44; p44/Mep50; RGD1310479 ; RP11 552M11.3; WD repeat containing protein 77; WD repeat domain 77 ; WD repeat-containing protein 77; WDR77
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Epigenetics and Nuclear Signaling; Signal transduction
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
37 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG
Available Sizes
Frequently Asked Questions
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