RASSF8 Polyclonal Antibody

This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t (12;22) (p11.2; q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

C12orf2; Carcinoma associated HOJ 1; Carcinoma associated protein HOJ 1; Carcinoma-associated protein HOJ-1; HoJ 1; HoJ1; Ras association (RalGDS/AF 6) domain family (N terminal) member 8; Ras association (RalGDS/AF 6) domain family 8; Ras association domain containing protein 8; Ras association domain family 8; Ras association domain-containing protein 8; RASF8; RASSF 8; Rassf8