AKAP7 Polyclonal Antibody

This gene encodes a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described.[

A-Kinase Anchoring Protein 7; A Kinase (PRKA) Anchor Protein 7; A-Kinase Anchor Protein 18 KDa; AKAP 18; AKAP15; AKAP18; Protein Kinase A-Anchoring Protein 7 Isoforms Alpha/Beta; Protein Kinase A-Anchoring Protein 7 Isoform Gamma.