TGFBI Polyclonal Antibody
Product Specifications
Background
TGFBI, also named as BIGH3, Kerato-epithelin and RGD-CAP, binds to type I, II, and IV collagens. TGFBI is an adhesion protein which may play an important role in cell-collagen interactions. In cartilage, it may be involved in endochondral bone formation. TGFBI is an extracellular matrix adaptor protein, it has been reported to be differentially expressed in transformed tissues. TGFBI is a predictive factor of the response to chemotherapy, and suggest the use of TGFBI-derived peptides as possible therapeutic adjuvants for the enhancement of responses to chemotherapy. Defects in TGFBI are the cause of epithelial basement membrane corneal dystrophy (EBMD) . Defects in TGFBI are the cause of corneal dystrophy Groenouw type 1 (CDGG1) . Defects in TGFBI are the cause of corneal dystrophy lattice type 1 (CDL1) . Defects in TGFBI are a cause of corneal dystrophy Thiel-Behnke type (CDTB) . Defects in TGFBI are the cause of Reis-Buecklers corneal dystrophy (CDRB) . Defects in TGFBI are the cause of lattice corneal dystrophy type 3A (CDL3A) . Defects in TGFBI are the cause of Avellino corneal dystrophy (ACD) .
Abbreviation
TGFBI
UniProt
Q15582
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Fusion protein of human TGFBI
Target
>RGD containing collagen associated protein; AI181842; AI747162; Beta ig; Beta ig h3; Beta ig-h3; BGH3; Big h3; BIGH3; CDB1; CDG2; CDGG1; CSD; CSD1; CSD2; CSD3; EBMD; Kerato epithelin; Kerato-epithelin; LCD1; MGC150270; RGD CAP; RGD-CAP; RGD-containing collagen-associated protein; TGFBI; TGFBI transforming growth factor; beta induced;68kDa; Transforming growth factor beta induced protein ig h3; Transforming growth factor-beta-induced protein ig-h3
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Developmental Biology; Neuroscience; Signal Transduction
Purification
Antigen affinity purification
Concentration
1.32 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:200
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/z5dmsc
Product MSDS
https://789.bio/eb/bfPyj9
Calculated Molecular Weight
75 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG
Available Sizes
Curated Selection
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