CAPN3 Polyclonal Antibody
Product Specifications
Background
Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed.
Abbreviation
CAPN3
UniProt
P20807
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Fusion protein of human CAPN3
Target
Calcium-activated neutral proteinase 3; calpain 3; (p94) ; Calpain L3; Calpain large polypeptide L3 ; Calpain p94; calpain p94; large [catalytic] subunit; calpain; large polypeptide L3; Calpain-3; CAN3; CANP 3; CANP3; CANPL3; CAPN3; LGMD 2A; LGMD2; LGMD2A; Lp82; Lp85; MGC10767; MGC11121; MGC14344; MGC4403; Muscle-specific calcium-activated neutral protease 3; muscle-specific calcium-activated neutral protease 3 large subunit; nCL-1; New calpain 1; p94
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cell Biology; Signal transduction
Purification
Antigen affinity purification
Concentration
1.4 mg/mL
Dilution
IHC 1:30-1:150
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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