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TP53 Polyclonal Antibody

Product Specifications

Background

TP53, also named as P53 and NY-CO-13, belongs to the p53 family. It has 9 isoforms. In SDS-Page, the MW is about 53kd. TP53 acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. It is involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. The antibody reacts specifically with 53 kDa protein.

Abbreviation

TP53

UniProt

P04637

Host

Rabbit

Reactivity

Human

Immunogen

Fusion protein of human TP53

Target

Antigen NY-CO-13; BCC7; Cellular tumor antigen p53; FLJ92943; LFS1; Mutant tumor protein 53; p53; p53 tumor suppressor; P53; Phosphoprotein p53; Tp53; Transformation related protein 53; TRP53; Tumor protein 53; Tumor protein p53; Tumor suppressor p53

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB

Field of Research

Cancer; Cell Biology; Epigenetics and Nuclear Signaling

Purification

Antigen affinity purification

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

44 kDa

Observed Molecular Weight

Refer to figures

Isotype

IgG

Available Sizes

Frequently Asked Questions

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