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KCNT1 Polyclonal Antibody

Product Specifications

Background

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a sodium-activated potassium channel subunit which is thought to function in ion conductance and developmental signaling pathways. Mutations in this gene cause the early-onset epileptic disorders, malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy. Alternative splicing results in multiple transcript variants.

Abbreviation

KCNT1

UniProt

Q5JUK3

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Synthetic peptide of human KCNT1

Target

BA100C15.2; EIEE14; ENFL5; KCa4.1; KCNT1; KCNT1; Potassium channel subfamily T member 1; Potassium channel; sodium activated subfamily T; member 1; Potassium channel; subfamily T; member 1 ; Sequence like a calcium-activated K+ channel; SLACK ; Slo2.2

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Neuroscience

Purification

Antigen affinity purification

Concentration

0.9 mg/mL

Dilution

IHC 1:30-1:150

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

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