L-Glutamic acid-13C5,15N

L-Glutamic acid-13C5,15N is the 13C- and 15N-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA) . L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.

Product Specifications

CAS Number

[202468-31-3]

UNSPSC

12352211

Target

Apoptosis; Endogenous Metabolite; Ferroptosis; iGluR; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Apoptosis; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/l-glutamic-acid-13c5-15n.html

Purity

99.9

Solubility

H2O : 31.25 mg/mL (ultrasonic)

Smiles

O[13C]([13CH2][13CH2][13C@H]([15NH2])[13C](O)=O)=O

Molecular Formula

13C5H9 15NO4

Molecular Weight

153.09

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Isoform

AMPA Receptor

Available Sizes

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