KCNN1 Polyclonal Antibody
Product Specifications
Background
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes.
Abbreviation
KCNN1
UniProt
Q92952
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide of human KCNN1
Target
HSK1 ; KCa2.1; KCNN 1; Kcnn1; KCNN1; Potassium intermediate/small conductance calcium activated channel subfamily N member 1; SK; SK1; SKCa 1; SKCa1; Small conductance calcium activated potassium channel protein 1; Small conductance calcium-activated potassium channel protein 1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Neuroscience
Purification
Antigen affinity purification
Concentration
1.56 mg/mL
Dilution
IHC 1:50-1:300
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Frequently Asked Questions
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