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PPY Polyclonal Antibody

Product Specifications

Background

This gene encodes a member of the neuropeptide Y (NPY) family of peptides. The encoded 95 aa preproprotein is synthesized in the pancreatic islets of Langerhans and proteolytically processed to generate two peptide products. These products include the active pancreatic hormone of 36 aa and an icosapeptide of unknown function. This hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Abbreviation

PPY

UniProt

P01298

Host

Rabbit

Reactivity

Human; Rat

Immunogen

Synthetic peptide of human PPY

Target

Pancreatic polypeptide; Pancreatic polypeptide Y; Pancreatic prohormone; PNP; PP; PPY; prepro-PP (prepropancreatic polypeptide)

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB

Field of Research

Cancer; Signal transduction

Purification

Antigen affinity purification

Concentration

2.28 mg/mL

Dilution

WB 1:1000-1:5000

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product Datasheet

https://789.bio/ea/cdumys

Product MSDS

https://789.bio/eb/84GWfL

Calculated Molecular Weight

11 kDa

Observed Molecular Weight

Refer to figures

Isotype

IgG

Available Sizes

Curated Selection

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