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ELP1 Polyclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. Alternative splicing results in multiple transcript variants encoding different isoforms.

Abbreviation

ELP1

UniProt

O95163

Host

Rabbit

Reactivity

Human

Immunogen

Synthetic peptide of human ELP1

Target

DKFZp781H1425; DYS; Dysautonomia (Riley Day syndrome hereditary sensory autonomic neuropathy type III) ; Elongator complex protein 1; ELP 1; ELP1; ELP1; FD; FLJ12497; IKAP; IkappaB kinase complex associated protein; IkappaB kinase complex-associated protein; ikbkap; IKI 3; IKI3; IKK complex associated protein; IKK complex-associated protein; Inhibitor of kappa light polypeptide gene enhancer in B cells kinase complex associated protein; OTTHUMP00000063889; p150; TOT 1; TOT1

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Epigenetics and Nuclear Signaling; Signal transduction

Purification

Antigen affinity purification

Concentration

0.9 mg/mL

Dilution

IHC 1:30-1:150

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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