BAG3 Polyclonal Antibody
Product Specifications
Background
Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70.
Abbreviation
BAG3
UniProt
O95817
Host
Rabbit
Reactivity
Human; Rat
Immunogen
Recombinant Human BAG3 protein expressed by E.coli
Target
BAG family molecular chaperone regulator 3 ; BAG-3; Bcl-2-associated athanogene 3; Bcl-2-binding protein Bis; BIS
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Cell Biology; Metabolism
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000
Buffer
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
62 kDa
Observed Molecular Weight
80 kDa
Isotype
IgG
Available Sizes
Curated Selection
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