Carboxypeptidase B2 Polyclonal Antibody
Product Specifications
Background
CPB2 (Carboxypeptidase B2; also CPU and TAFI) is a secreted,50-60 kDa glycoprotein member of the peptidase M14 family of enzymes. It is expressed by hepatocytes (60 kDa) and platelets (50 kDa), with MW differences attributable to glycosylation. CPB2 is cleaved by thrombin and plasmin, generating a 36 kDa, relatively insoluble nonglycosylated enzymatically active fragment (TAFIa) .
Abbreviation
CPB2
UniProt
Q96IY4
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human CPB2 protein expressed by E.coli.
Target
Carboxypeptidase B2; Carboxypeptidase U; CPU; Plasma carboxypeptidase B; pCPB; Thrombin-activable fibrinolysis inhibitor; TAFI; CPB2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cardiovascular; Signal Transduction; Metabolism
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
WB 1:250-1:500
Buffer
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
48 kDa
Observed Molecular Weight
56 kDa
Isotype
IgG
Available Sizes
Documents
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